DL-Propargylglycine, cystathionine gamma-lyase inhibitor

Code: P7888-1G D2-231

Biochem/physiol Actions

DL-Propargylglycine (PAG) is an irreversible inhibitor of the enzyme cystathionine γ-lyase (GCL), a key enzyme involved in glutathione synthesis and t...


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Biochem/physiol Actions

DL-Propargylglycine (PAG) is an irreversible inhibitor of the enzyme cystathionine γ-lyase (GCL), a key enzyme involved in glutathione synthesis and the metabolic transsulfuration pathway which regulates homocysteine concentration and mediates cysteine synthesis. Treatment of animal disease models with PAG was shown to alleviate symptoms of diseases that impair the formation or action of hydrogen sulfide (H2S).

application(s)cell analysis
assay≥98% (TLC)
colorwhite
formpowder
InChI keyDGYHPLMPMRKMPD-UHFFFAOYSA-N
InChI1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)
Quality Level200
SMILES stringNC(CC#C)C(O)=O
storage temp.−20°C
Cas Number64165-64-6
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